Universität Bonn




Becker, J., A. Schleinitz, C. Hermsen; S. Rappold, P. Saftig, A. Jeschke & A. Haas (2023) Rab GTPase regulation of phagosome-lysosome fusion is bypassed in the presence of micromolar Ca2+. Journal of Cell Science 136: jcs260806. Doi: 10.1242/jcs.260806

Hansen, P., T. Haubenthal, C. Reiter, J. Kniewel, K. Bosse-Plois, K. von Bargen & A. Haas (2023) Differential effects of Rhodococcus equi virulence-associated proteins (Vaps) on macrophages and artificial lipid membranes. Microbiological Spectrum 11: e0341722. Doi: 10.1128/spectrum.03417-22

Haubenthal, T., P. Hansen, I. Krämer, M. Gindt, A. Jünger-Leif, O. Utermöhlen & A. Haas (2023) Specific preadaptations of Rhodococcus equi cooperate with its Virulence-associated protein A during macrophage infection. Molecular Microbiology 119: 285-301. Doi: 10.1111/mmi.15026

Jeschke, A. & Haas, A. (2023) Biochemically reconstituted fusion of phagosomes and endosomes with lysosomes. Methods in Molecular Biology 2692: 247-259. Doi: 10.1007/978-1-0716-3338-0_17.

Jeschke, A. (2023) An in vitro system to analyze generation and degradation of phagosomal phosphatidylinositol phosphates Methods in Molecular Biology 2692: 261-274. Doi: 10.1007/978-1-0716-3338-0_18

Schleinitz, A., L.A. Pöttgen, T. Keren-Kaplan, J. Pu, P. Saftig, J.S. Bonifacino, A. Haas & A. Jeschke (2023) Consecutive functions of small GTPases guide HOPS-mediated tethering of late endosomes and lysosomes. Cell Reports 42: 111969

Geerds, C., A. Haas & H.H. Niemann (2021) Conformational changes of loops highlight a potential binding site in Rhodococcus equi VapB. Acta Crystallographica Section F 77: 246-253

Hansen, P., K. von Bargen, A. Juenger-Leif & A. Haas (2022) Laboratory plasticware induces expression of a bacterial virulence factor. mSphere: e0031122 (“Editors’ Choice”)

Frankfater, C., W.R. Henson, A. Juenger-Leif, M. Foston ,T.S. Moon, J. Turk, J.L. Kao, A. Haas and F.F. Hsu (2020) Structural Determination of a New Peptidolipid Family from Rhodococcus opacus and the Pathogen Rhodococcus equi by Multiple Stage Mass Spectrometry. Journal of the American Society for MassSpectrometry 31: 611-623

von Bargen, K., M. Scraba, I. Krämer, M .Ketterer, C. Nehls, S. Krokowski, U. Repnik, M. Wittlich, A. Maaser, P. Zapka, M. Bunge, M. Schlesinger, G. Huth, A. Klees, P. Hansen, A. Jeschke, G. Bendas, O. Utermöhlen, G. Griffiths, T. Gutsmann, J. Wohlmann and A. Haas (2018) VapA from Rhodococcus equi is an inter-compartmental pH-neutralising virulence factor. Cellular Microbiology 21: e12958

Pelka, K., D. Bertheloot, E. Reimer, K. Phulphagar, S.V. Schmidt, A. Christ, R. Stahl, N.  Watson, K. Miyake, N. Hacohen, A. Haas, M.M. Brinkmann, A. Marshak-Rothstein, F. Meissner and E. Latz (2018) The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport. Immunity 48: 911-922.
Jeschke, A. and A. Haas (2018) Sequential actions of phosphatidylinositol phosphates regulate phagosome-lysosome fusion. Molecular Biology of the Cell 29: 452-465

Haas, A., M. Hensel, A. Lührmann, T. Rudel and U.E. Schaible (2018) Intracellular compartments of pathogens: Highways to hell or stairways to heaven? International Journal of Medical Microbiology 308: 1-2

Kissing, S., P. Saftig and A. Haas (2018) Vacuolar ATPase in phago(lyso)some biology. International Journal of Medical Microbiology 308: 58-67

Patin, E.C., A.C. Geffken, S. Willcocks, C. Leschczyk, A. Haas, F. Nimmerjahn, R. Lang, T.H. Ward and U.E. Schaible (2017) Trehalose dimycolate interferes with Fc(gamma)R-mediated phagosome maturation through Mincle, SHP-1 and FcγRIIB signalling. PLoS One 12: e0174973

Jeschke, A., N. Zehethofer, D. Scwhudke and A. Haas (2016) Quantification of phosphoinositol phosphate species in purified membranes. Methods in Enzymology 587: 271-291

Kissing, S., S. Rudnik, M. Damme, R. Lüllmann-Rauch, A. Ichihara, U. Kornak, E.L. Eskelinen, S. Jabs, J. Heeren, J. De Brabander, A. Haas and P. Saftig (2016) Disruption of the v-H+-ATPase complex in liver causes mTORC1-independent accumulation of autophagic vacuoles and lysosomes. Autophagy 13: 670-685

Saftig, P. and A. Haas (2016) Turn up the lysosome. Nature Cell Biology 18: 1025-1027

Jeschke, A. and A. Haas (2016) Deciphering the role of phosphoinositide lipids in phagolysosome biogenesis. Communicative & Integrative Biology 9: e1174798

Klionsky, D., K. Abdelmohsen, A. Abe, … A. Haas, ... S.M. Zughaier (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12: 1-222

Kissing, S., C. Hermsen, U. Repnik, C.K. Nesset, von Bargen, K., G. Griffiths, A. Ichihara, B. Lee, M. Schwake, J. De Brabander, A. Haas and P. Saftig (Shared last authorship) (2015) Vacuolar ATPase in phagosome-lysosome fusion. Journal of Biological Chemistry 290: 14166-14180

Jeschke, A., N. Zehethofer, B. Lindner, J. Krupp, D. Schwudke, I. Haneburger, M. Jovic, J.M. Backer, T. Balla, H. Hilbi and A. Haas (2015) Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis. Proceedings of the National Academy of Sciences USA 112: 4636-4641

Grimm, C., L. M. Holdt, C. C. Chen, S. Hassan, C. Müller, S. Jörs, H. Cuny, S. Kissing, B. Schröder, E. Butz, B. Northoff, J. Castonguay, C. A. Luber, M. Moser, S. Spahn, R. Lüllmann-Rauch, C. Fendel, N. Klugbauer, O. Griesbeck, A. Haas, M. Mann, F. Bracher, D. Teupser, P. Saftig, M. Biel and C. Wahl-Schott (2014) High susceptibility of fatty liver disease in two-pore channel 2 deficient mice. Nature Communications 5: 4699

Geerds, C., J. Wohlmann, A. Haas and H.H. Neumann (2014) Structure of Rhodococcus equi virulence-associated protein B (VapB) reveals an eight-stranded antiparallel beta-barrel consisting of two Greek-key motifs. Acta Crystallographica Section 70: 866-871

Kasper, L., K. Seider, F. Gerwien, S. Allert, S. Brunke, T. Schwarzmüller, L. Ames, C. Zubiria-Barrera, M.K. Mansour, U. Becken, D. Barz, J.M. Vyas, M. Reiling, A. Haas, K. Haynes, K. Kuchler and B. Hube B (2014) Identification of Candida glabrata genes involved in pH modulation and modification of the phagosomal environment in macrophages. PLoS One 9: e96015

Sydor, T.,K. von Bargen, F.F. Hsu, G. Huth, O. Holst, J. Wohlmann, U. Becken, T. Dykstra, K. Söhl, B. Lindner, J.F. Prescott, U.E. Schaible, O. Utermöhlen and A. Haas A (2013) Diversion of phagosome trafficking by pathogenic Rhodococcus equi depends on mycolic acid chain length. Cellular Microbiology 15: 458-473.

Ulbricht, A., F.J. Eppler, V.E: Tapia, P.F. van der Ven, N. Hampe, N. Hersch, P. Vakeel, D. Stadel, A. Haas, P. Saftig, C. Behrends, D.O. Fürst, R. Volkmer, B. Hoffmann, W. Kolanus and J. Höhfeld (2013) Cellular Mechanotransduction Relies on Tension-Induced and Chaperone-Assisted Autophagy. Current Biology 23: 430-435

Jeschke, A., U. Becken and A. Haas (2012) In vitro veritas – Phagosomenreifung im Reagenzglas. BIOspektrum, 18: 268-270.

Zehner, M., J. Rauen, A. I. Chasan, M. Embgenbroich, M.G. Camps, S. Kaden, A. Haas, C. Kurts, E. Endl, M. Beyer, H.J. Gröne, F. Ossendorp and S. Burgdorf (2012)

Intra-endosomal flow cytometry: a novel approach to analyze the protein composition of antigen-loaded endosomes. European Journal of Immunology, 42: 2187-2190.

Hilbi, H. and A. Haas A (2012) Secretive Bacterial Pathogens and the Secretory Pathway. Traffic, 13: 1187-1197.

Hsu, F.F., J. Wohlmann, J. Turk and A. Haas (2011) Structural definition of trehalose 6-monomycolates and trehalose 6,6'-dimycolates from the pathogen Rhodococcus equi by multiple-stage linear ion-trap mass spectrometry with electrospray ionization. Journal of the American Society for Mass Spectrometry 22: 2160-2170

Seider, K., S. Brunke, L. Schild, N. Jablonowski, D. Wilson, O. Majer, D. Barz, A. Haas, K. Kuchler, M. Schaller and B. Hube (2011) The facultative intracellular pathogen Candida glabrata subverts macrophage cytokine production and phagolysosome maturation. Journal of Immunology 187: 3072-3086.

von Bargen, K., J. Wohlmann, G. A. Taylor, O. Utermöhlen and A. Haas (2011) Nitric oxide-mediated intracellular growth restriction of pathogenic Rhodococcus equi can be prevented by iron. Infection and Immunity, 79: 2098-2111.

Hsu, F.-F., K. Soehl, J. Turk and A. Haas (2011) Characterization of mycolic acids from the pathogen Rhodococcus equi by tandem mass spectrometry with electrospray ionization. Analytical Biochemistry 409: 112-122

Becken, U., A. Jeschke, K. Veltman and A. Haas (2010) Cell-free analysis of macrophage phagosome-lysosome fusion. Proceedings of the National Academy of Sciences USA 107: 20726-20731

Dykstra, T., O. Utermoehlen and A. Haas (2010) Defined particulate ligands trigger specific cell autonomous defense mechanisms of macrophages. Innate Immunity 17: 388-402

Schueller, C., F. Quinn and A. Haas (2010) The Afipia toolbox: Mutational analysis and recombinant gene expression. FEMS Microbiology Letters, 302: 203-210



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Prof. Dr. Albert Haas


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